MyBioSource.com's UPF2 Antibody (Center) is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Flow Cytometry, and Western Blot. The UPF2 Antibody (Center) was generated using smg-3 as the antigen and it reacts with Human.
Description
UPF2 is a protein that is part of a
post-splicing multiprotein complex involved in both mRNA nuclear
export and mRNA surveillance. mRNA surveillance detects exported
mRNAs with truncated open reading frames and initiates
nonsense-mediated mRNA decay (NMD). When translation ends upstream
from the last exon-exon junction, this triggers NMD to degrade
mRNAs containing premature stop codons. This protein is located in
the perinuclear area. It interacts with translation release factors
and the proteins that are functional homologs of yeast Upf1p and
Upf3p